Granulation is one of the most important unit operations in the production of pharmaceutical oral dosage forms. However, there are many different technologies each having different strengths and weaknesses. Most companies choose which one to use simply based on their own experience. This article introduces different processes, compares them objectively and offers unbiased advice on the merits of each system. It then looks at the implications of selection on two different applications.
by Dr. Harald Stahl
Senior pharmaceutical technologist at
GEA Pharma Systems
Mauchener Strasse 14,
D-79379 Müllheim, Germany
Tel. +49 7631 701 614
Fax +49 7631 701 669
harald.stahl@geapharmasystems.com
This technical article was first publish in the journal Pharmaceutical Technology Europe in November 2004, if you like to read the complete article online please follow the link or download the attached file.
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