Built-in versatility for the pharmaceutical industry
The MULTI-PROCESSOR™ sets the versatility standard. Available in a range of sizes to meet customer requirements - from the MP-MICRO™ development unit to full-scale production equipment - it maximises flexibility by enabling users to attach modules to the central fluid bed for specific functions: blending, granulating, drying, pelletizing, and coating. The MULTI-PROCESSOR™ is the ideal instrument for formulation, process development, production of clinical material, through to full-scale production.
Process Modules
Blending & Granulating, Drying, Pelletizing and Coating
The MULTI-PROCESSOR™ offers both a spray dryer granulator and a top spray granulator. A pelletizing module and PRECISION COATER™, are the solution to forming, pelletizing and coating particles of varying sizes.
Drying
Warm air is blown through a perforated distributor to rapidly and gently dry materials until the required residual moisture content is reached. Moisture evaporated from the product is exhausted with the drying air.
Special features
- Selection of air distributors
- Short process time
Top Spray GranulatorThe top spray granulator agglomerates finer particles into larger, free flowing granulates in a one-pot process. Ingredients are mixed and pre-heated by an upward flow of heated air. Granulation occurs by spraying liquid into the fluidized powder. The granules are subsequently dried with heated air. The top spray granulator can also be used for top spray coating, layering from liquids, and instantizing.
Special features
- One pot process
- Selection of air distributors
Spray Dryer Granulator
The spray dryer granulator transforms suspensions or solutions into dry, free-flowing, dustless granules. A suspension or solution of the substance to be dried is sprayed onto warm air, simultaneously drying and agglomerating the product. Batch or continuous discharge is available - in the continuous mode, the product is discharged at a controlled rate to maintain an optimum bed height.
Special features
- Compact unit
- Easy scale-up
- Batch or continuous discharge
Precision-Granulator™
A rotating high velocity air stream is established in the central agglomeration tube. Particles are picked up at the base of the tube and accelerated by the air stream. The particles come into contact with liquid droplets produced from the spray nozzle at the base of the tube \ the relative velocity of air, liquid droplets and particles are high so wetting is efficient and drying begins almost immediately. Most of the feed material is in the outer “holding area”, where the gas velocity is very low. Attrition is greatly reduced. The gas humidity is also low in the holding area so the material is dry not sticky. Individual particles may make repeated cycles (typically from 10 to 1,000) through the tube, allowing very large agglomerates to be built up.
Precision-Coater™
The Precision-Coater™i s used for smaller particles, such as powders, granules, seeds, crystals, pellets, and small tablets.The product is coated and partially dried by being blown upward through a central column with atomized liquid and drying air. The material falls into the outer part of the container where heated air completes the drying process. On reaching the air distributor at the base of the module, the product flows again into the central column for further coating.This process continues until the specified degree of coating is obtained.
Special features
- High spray rates for short processes
- Highly controlled product movement
- Minimal agglomeration or granulation